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Recent Publications

Quantification of neonatal lung parenchymal density via ultrashort echo time MRI with comparison to CT.  Higano NS, Fleck RJ, Spielberg DR, Walkup LL, Hahn AD, Thomen RP, Merhar SL, Kingma PS, Tkach JA, Fain SB, Woods JC. J Magn Reson Imaging. 2017 Feb 3. doi: 10.1002/jmri.25643. [Epub ahead of print]

Magnetic Resonance Imaging of Disease Progression and Resolution in Transgenic Mouse Model of Pulmonary Fibrosis. Cleveland ZI, Zhou YM, Akinyi TG, Dunn RS, Davidson CR, Guo J, Woods JC, Hardie WD.  Am J Physiol Lung Cell Mol Physiol 2016 (in press).

What makes a good pediatric transplant lung:  insights from in-vivo lung morphometry with hyperpolarized ³He MRI. Fishman EF, Quirk JD, Sweet SC, Woods JC, Gierada DS, Conradi MS, Siegel MJ, Yablonskiy DA. Pediatric Transplantation 2017 (in press).

Ultrashort Echo-Time Magnetic Resonance Imaging Is a Sensitive Method for the Evaluation of Early Cystic Fibrosis Lung Disease.  Roach DJ, Crémillieux Y, Fleck RJ, Brody AS, Serai SD, Szczesniak RD, Kerlakian S,  Clancy JP, Woods JC. Ann Am Thorac Soc 2016; 13: 1923-1931.

Hyperpolarized 129Xe for investigation of mild cystic fibrosis lung disease in pediatrics.  Thomen RP, Walkup LL, Roach DJ, Cleveland ZI, Clancy JP, Woods JC. J Cyst Fibr 2016, Jul 28. pii: S1569-1993(16)30565-3.

Quantitative CT characterization of pediatric lung development using routine clinical imaging.  Stein JM, Walkup LL, Brody AS, Fleck RJ, Woods JC.  Pediatric Radiology 2016; 46: 1804-1812.

Morphological and quantitative evaluation of emphysema in chronic obstructive pulmonary disease patients: A comparative study of MRI with CT.  Roach DJ, Crémillieux Y, Serai SD, Thomen RP, Wang H, Zou Y, Szczesniak RD, Benzaquen S, Woods JC.  J Magn Reson Imag 2016; 44: 1656-1663.

Feasibility, tolerability, and safety of pediatric hyperpolarized ¹²⁹Xe magnetic resonance imaging in healthy volunteers and subjects with cystic fibrosis.  Walkup LL, Thomen RP, Akinyi T, Watters E, Ruppert K, Clancy JP, Woods JC, Cleveland ZI. Pediatric Radiology 2016, 46: 1651-1662.

Retrospective respiratory self-gating and removal of bulk motion in pulmonary UTE MRI of neonates and adults.  Higano NS, Hahn AD, Tkach JA, Cao X, Walkup LL, Thomen RP, Merhar SL, Kingma PS, Fain SB, Woods JC.  Magn Reson Med. 2016 Mar 12. doi: 10.1002/mrm.26212.

A novel switched frequency 3He/1H high-pass birdcage coil for imaging at 1.5 Tesla. Pratt R, Giaquinto R, Ireland C, Daniels B, Loew W, Higano NS, Cao X, Thomen RP, Woods JC, Dumoulin CL. Concepts Magn Reson B. 2015 Oct 6. doi: 10.1002/cmr.b.21309.

Pulmonary MRI of neonates in the intensive care unit using 3D ultrashort echo time and a small foot-print MRI system.  Hahn AD, Higano NS, Walkup LL, Thomen RP, Cao X, Merhar SL, Tkach JA, Woods JC, Fain SB. J Magn Reson Imag J Magn Reson Imaging. 2017 Feb;45(2):463-471.

Newer Imaging Techniques for Bronchopulmonary Dysplasia.  Walkup LL, Woods JC.  Clin Perinatol. 2015 Dec;42(4):871-87. doi: 10.1016/j.clp.2015.08.012. Epub 2015 Sep 26. Review.

Modeling pulmonary alveolar microlithiasis by epithelial deletion of the Npt2b sodium phosphate cotransporter reveals putative biomarkers and strategies for treatment.  Saito A, Nikolaidis NM, Amlal H, Uehara Y, Gardner JC, LaSance K, Pitstick LB, Bridges JP, Wikenheiser-Brokamp KA, McGraw DW, Woods JC, Sabbagh Y, Schiavi SC, Altinişik G, Jakopović M, Inoue Y, McCormack FX.  Sci Transl Med. 2015 Nov 11;7(313):313ra181. doi: 10.1126/scitranslmed.aac8577.

Experimental Evidence of Age-Related Adaptive Changes in Human Acinar Airways.  Quirk JD, Sukstanskii AL, Woods JC, Lutey BA, Conradi MS, Gierada DS, Yusen RD, Castro M, Yablonskiy DA.  J Appl Physiol (1985). 2015 Nov 5:jap.00541.2015. doi: 10.1152/japplphysiol.00541.2015. [Epub ahead of print]

Quantitative Magnetic Resonance Imaging of Bronchopulmonary Dysplasia in the Neonatal Intensive Care Unit Environment.  Walkup LL, Tkach JA, Higano NS, Thomen RP, Fain SB, Merhar SL, Fleck RJ, Amin RS, Woods JC.  Am J Respir Crit Care Med. 2015 Nov 15;192(10):1215-22. doi: 10.1164/rccm.201503-0552OC.

Localization and stretch-dependence of lung elastase activity in development and compensatory growth. Young SM, Liu S, Joshi R, Batie MR, Kofron M, Guo J, Woods JC, Varisco BM. J Appl Physiol (1985). 2015 Apr 1;118(7):921-31. doi: 10.1152/japplphysiol.00954.2014. Epub 2015 Jan 22.

Heterogeneity of specific gas volume changes: a new tool to plan lung volume reduction in COPD.  Salito C, Barazzetti L, Woods JC, Aliverti A.  Chest. 2014 Dec;146(6):1554-65. doi: 10.1378/chest.13-2855.

Biomedical imaging with hyperpolarized noble gases.  Ruppert K.  Rep Prog Phys. 2014 Nov;77(11):116701. doi: 10.1088/0034-4885/77/11/116701. Epub 2014 Oct 31. Review.

Regional ventilation changes in severe asthma after bronchial thermoplasty with (3)He MR imaging and CT.  Thomen RP, Sheshadri A, Quirk JD, Kozlowski J, Ellison HD, Szczesniak RD, Castro M, Woods JC.  Radiology. 2015 Jan;274(1):250-9. doi: 10.1148/radiol.14140080. Epub 2014 Aug 19.

Imaging mouse lung allograft rejection with (1)H MRI.  Guo J, Huang HJ, Wang X, Wang W, Ellison H, Thomen RP, Gelman AE, Woods JC.  Magn Reson Med. 2015 May;73(5):1970-8. doi: 10.1002/mrm.25313. Epub 2014 Jun 20.

Translational applications of hyperpolarized 3He and 129Xe.  Walkup LL, Woods JC.  NMR Biomed. 2014 Dec;27(12):1429-38. doi: 10.1002/nbm.3151. Epub 2014 Jun 23. Review.

Assessment of regional lung function with multivolume (1)H MR imaging in health and obstructive lung disease: comparison with (3)He MR imaging.  Pennati F, Quirk JD, Yablonskiy DA, Castro M, Aliverti A, Woods JC.  Radiology. 2014 Nov;273(2):580-90. doi: 10.1148/radiol.14132470. Epub 2014 Jun 15.